Find My Footwear

Just Run!

  • Running Shoes
    • Running Shoe Reviews
    • Running Shoe Comparisons
  • Shoe Guides
  • Walking Shoes
  • Work Shoes
  • Plantar Fasciitis
  • Flat Feet
  • Blog

Brooks Glycerin GTS 22 Review – High Stack Cushioned Support

Last Updated: November 17, 2025

By Paul Freary  

When it comes to cushioning, the Glycerin from Brooks has, for many years, been their premium offering. Known for a plush ride and deep midsole, the Glycerin always offers a luxurious level of shock absorption.

While the Glycerin Max takes the top spot this year in terms of out-and-out midsole stack, the Glycerin still provides a high level of cushioning and retains a soft, premium feel.

The cushioning here, in the Glycerin GTS 22, is the same as that in the Glycerin 22; only here, we have the addition of the brand’s Go-To-Support (GTS) to help control pronation and provide additional rearfoot stability.

If you click, or buy from, links on this page, we may receive compensation.  Learn more

Glycerin GTS 22

Glycerin GTS 22

Stats
Design
Fit
Performance
Shoes Like the Glycerin GTS 22
My Verdict

Stats

Brooks

Glycerin GTS 22

Best for

Daily trainer for those seeking a great combination of cushioning and support

Support

Neutral

Cushion

High stack cushioning with support

Stack Height

38mm heel
28mm forefoot

Drop

10mm

Weight 

Men 289g (10.2oz)

Women 257g (9.1oz)

Suggested Retail Price

$165

Fit

True to size

Rating

9.5/ 10

Design

The Glycerin GTS 22 from Brooks represents the brand’s premium features in terms of cushioning and control. From top to bottom, the show features some of the best features, not just from the brand, but also from the whole market.

The DNA Tuned, nitrogen-infused midsole utilises a twin-density midsole for cushioning and propulsion.

Glycerin GTS 22 Toe Box

During the injection moulding process, larger cells are formed in the rear of the midsole to create a softer landing. At 38mm thick, it’s also a near-max stack unit, meaning even heavier runners are catered for sufficiently.

In the forefoot, small cells create a more responsive feel, which combines with the forefoot rocker for a smooth and efficient toe-off that works at any pace.

Glycerin GTS 22 Heel Side

Support comes by way of Brooks’ GuideRails technology. These ‘rails’ are extensions of the midsole in the rearfoot that extend up around the heel. Creating a cup-like structure for the heel, they ensure the foot remains neutrally centred within the shoe’s cushioning.

The upper has a double jacquard mesh construction, which provides an excellent fit with a small degree of stretch that helps the shoe feel snug without being overly tight. There is ample padding in the tongue, ankle collar and Achilles area, which all contribute to a premium fit and feel.

Glycerin GTS 22

Glycerin GTS 22

Shop Now at

  • Amazon
  • Zappos
  • REI

Fit

The fit of the Glycerin GTS 22 is true to size in terms of length and is a little wider in the forefoot. The extra width in the forefoot is compared to models like the Ghost and Adrenaline from Brooks.

Glycerin GTS 22 Heel Rear

The extra width comes from a combination of both the actual width of the midsole of the shoe and the ‘stretch’ of the mesh upper. Together, this provides a little extra ‘wiggle room’ in the toe box.

Check Out My 6 Best Support Shoes Here

Performance

The ride of the Glycerin GTS 22 is excellent from the very first outing. The nitrogen-infused DNA Tuned cushioning does an excellent job of absorbing impact and providing a smooth, responsive toe off.

Glycerin GTS 22 Midsole

Support is excellent from the combination of elements that contribute to the control. The broader base and softer nitrogen-infused foam in the centre of the rearfoot allow the foot to ‘sink’ into the centre of the midsole. When combined with the GuideRails, any instability is quickly reduced, and the foot is held neutrally and naturally.

On push-off, the midsole provides a nice ‘spring’ that makes for a smooth and natural feeling. It’s not ‘racing shoe propulsion’, but just enough to maintain your effort.

Glycerin GTS 22 Heel Collar

The great-fitting upper contributes to the overall feel and ride of the shoe, and it’s clear from the moment you pull the shoes on that they are a premium-level model.

Durability is excellent from the Glycerin GTS 22, too. I have had a pair in my shoe rotation for almost 12 months now, and they really do show no signs of wear or midsole compression.

Glycerin GTS 22 Outsole
RUNNING SHOES Best Sellers on AMAZON

Shoes Like the Glycerin GTS 22

As a support category running shoe, competitors to the Glycerin GTS 22 are those which aim to offer higher levels of cushioning alongside control.

New Balance 860v14

The most popular models would include the New Balance 860v14, although this is probably more closely comparable to the Brooks Adrenaline GTS than the more premium Glycerin model.

That said, the New Balance does offer good levels of cushioning and support, but the cushioning, Fresh Foam X doesn’t quite have the same level of cushioning, responsiveness and durability as the Glycerin.

Saucony Hurricane 25

The Saucony Hurricane is Saucony’s premium control shoe, featuring the PWRRUN foam similar to that used in their performance models. While the Saucony is a very excellent option, I feel the Brooks just edges it in the key areas of overall cushioning feel, level of support and long-term durability.

Hoka Gaviota 5

From HOKA, the Gaviota is their premium support offering, but again, when standing side by side with the Glycerin is let down by its CM-EVA midsole, which feels a little outdated compared to the Brooks nitrogen-infused DNA Tuned cushioning.

My Verdict

The Glycerin GTS 22 is an excellent shoe. Such is its level of cushioning and control that, despite its higher price compared to the brand’s Adrenaline GTS model, which is around 20% cheaper, I have found the majority of customers opting for the Glycerin.

Glycerin GTS 22 Upper

Where the Adrenaline was always the more popular option, in part thanks to its lower price, the Glycerin has been winning fans since its launch.

RUNNING SHOES Best Sellers on AMAZON

As an all-around daily trainer for those requiring stability, I think it’s the best shoe on the market right now.

Author

  • Paul Freary
    Paul Freary

    Paul has a lifetime of running experience. As an athlete, he competed at the international level and has some pretty impressive PR’s.

    He lives in Lancashire in the UK and writes for several leading publications including Athletics Weekly.

    View all posts

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Logo Findmyfootwear Orng Txt

cushioned running shoes
 

runnng shoes
 

running shoes flat feet
 

running shoes for heavy runners
 

 

stability runnng shoes
 

wide running shoes wide feet
 

asics running shoes
 

daily trainers
 

 Brooks running shoes
 

saucony running shoes
 

new balance running shoes
 

hoka runnng shoes
 

on running shoes
 

carbon plated running shoes
 

 running shoes for 5k races
 

running shoes for walking
 

trail running shoes
 

high arch running shoes
 

waterproof running shoes
 

zero drop running shoes
 

winter running shoes
 

Find My Footwear

818 Dominick Ct, South Plainfield, NJ 07080

Phone : 862-256-7108

________________________________

  • About Us
  • Contact Us
  • Disclaimer
  • Privacy Policy
  • Sitemap
  • Terms of Service

The information on this site is for informational purposes only and should not be considered as medical advise or a  substitute for professional advice

Follow us on our Social Network

Facebook
X (Twitter)
Pinterest
LinkedIn
Instagram

Affiliate Disclosure

FindMyFootwear.com is a participant in the Amazon Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com

FindMyFootwear.com also participates in various other affiliate programs, and we sometimes get a commission for purchases made through our links.

Copyright © 2025 Findmyfootwear.com