By Paul Freary
Enter your The ASICS Gel Kayano 33 is the brand’s most popular and indeed range-topping structured-cushioned shoe. The Brooks Adrenaline GTS 25, while not the brand’s range-topping model in the category, is their most popular shoe of this type and most established in their lineup.
Both models offer a combination of cushioning and structured support to control over-pronation.
Here we’ll look at how these two popular running shoes compare and which you should choose as your next daily-training, supportive shoe.here...
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Kayano 33 and Adrenaline GTS 25
Stats
Running Shoes | Kayano 33 | Adrenaline GTS 25 |
|---|---|---|
Best for | Premium cushioned structured daily trainer | Good value, support and control |
Support | Structured Support | Structured Support |
Cushion | High stack with control | Mid/High stack cushioning with support |
Stack Height | 40mm heel | 36mm heel |
Drop | 8mm | 10mm |
Weight | Men 298g (10.5oz) Women 259g (9.2oz) | Men 300g (10.6oz) |
Suggested Retail Price | $170 | $155 |
Fit | True to size | True to size |
Rating | 9/ 10 | 8.5/ 10 |
Design
Support
In the Adrenaline GTS 25, the GTS stand for ‘Go To Support’, or, as Brooks is shifting towards for 2026, GuideRail Technology System.
The GuideRails are extensions of the cushioning in the rearfoot of the shoe that extend up around the heel on both the medial and lateral sides of the midsole cushioning. In the Adrenaline GTS 25, a new manufacturing process co-moulds the GuideRails in one piece with the midsole cushioning. This results in a smoother, more natural feeling level of support.

Kayano 33 and Adrenaline GTS 25 - Midsoles
These have the effect of keeping the foot central within the shoe and in a more neutral position. The GuideRail system is highly effective and helps keep overpronators in a neutral position.
The support now used in the Kayano 33 is the new FLUIDSUPPORT technology system. The 4D control of the last couple of generations, with its ‘responsive posting’, has been updated to a system which aims to adapt to the varying biomechanical needs of runners, providing guidance while allowing a natural foot motion for smooth, efficient transitions throughout the gait cycle.
Cushioning
The Adrenaline GTS 25 features Brooks’ DNA Loft V3 nitrogen-infused foam midsole. Now widely used across the brand’s range, nitrogen-infused midsoles offer high-quality, responsive cushioning that proves to be very durable.

Adrenaline GTS 25 vs Kayano 33 - Heel Stack
The Adrenaline GTS 25 has more cushioning than its predecessor, with 3mm more nitrogen foam cushioning in the forefoot compared to the GTS 24, and 1mm more in the heel. The shoe has a higher stack height as a result, but the heel-toe drop has been reduced from 12mm to 10mm. These changes result in a more cushioned, softer and balanced ride.
The Kayano also uses a new combination of midsole foams with FF BLAST PLUS and FF BLAST MAX in the midsole. As used in existing shoes in the ASICS range, both are proven and popular materials which provide control with a smooth, responsive feel.
The combination of the FF BLAST PLUS and FF BLAST MAX foams work in a similar manner to a dual-density midsole construction, with the slightly firmer foam featuring more on the medial side of the shoe to smoothly reduce pronation.
A new, softer, updated version of PUREGEL features in the heel of the shoe and is approximately 65% softer vs standard GEL technology.

Kayano 33
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Adrenaline GTS 25
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Fit
Both the Kayano and Adrenaline are true-to-size in terms of length and width and fit the same as other models from the respective brands.

Kayano 33 and Adrenaline GTS 25
The upper of both shoes is high-quality and somewhat plush in construction. Both have a nice, small amount of stretch to them and provide a good degree of ‘wiggle-room’, accommodating varying widths of feet with ease.
Both models are also available in width-fitting options for both men and women.
Performance
It is clear that the Kayano is the more premium of these two popular support models, and it is in the ride of the Kayano 33 where this is most obvious. The use of the dual layers of foam does an excellent job of absorbing impact and naturally controlling pronation.
The support in the Kayano goes largely unnoticed, but that’s to its credit. It does a great job of providing a reasonably high degree of control smoothly and effectively.

Adrenaline GTS 25 and Kayano 33 - Heel Collar
Overall cushioning is excellent, and although the Kayano isn’t the most responsive shoe, this model is primarily about support and cushioning during daily training miles.
The Adrenaline GTS25 has good cushioning properties in its own right, but it does feel a little firmer next to the Kayano. There is perhaps a slightly higher degree of spring to the forefoot on toe-off, but again, these are primarily easy running shoes rather than performance models.

Kayano 33 and Adrenaline GTS 25 - Heel
The support in this Adrenaline is a little less effective than it was in the previous generation model. The co-moulded design of the GuideRails is perhaps the reason. Being of the same density as the rest of the midsole (for me) reduces the level of control a little.
While for most, the GuideRails will prove to offer enough support, in the previous version, the support handled maybe 90% of runners who pulled it on. Here, that’s reduced to around 70%.

Adrenaline GTS 25 and Kayano 33 - Uppers
Long-term performance of the Adrenaline is excellent; once again, the DNA Loft v3 foam is proving to keep on providing ample cushioning for many miles.
This combination of foams is new to the Kayano, but for me, in other models, long-term performance does seem to dull in the later stages of the shoe’s life. For many, this won’t be noticed or indeed an issue.
My Verdict
While the Adrenaline is a great shoe, when compared against the Kayano, strictly considering performance, it is ultimately the Kayano which comes out on top. And so it should if we are honest, as it’s considerably more expensive.

Kayano 33 and Adrenaline GTS 25
The Adrenaline does provide good competition, and if we were to consider cost into the equation, the pound-for-pound performance would place these two equally.
The Kayano offers a simply plushier, smoother and more balanced ride.
The Adrenaline is perhaps more durable and offers more in that respect, but its level of support is now a little less effective than that offered by the Kayano. Scoring the two shoes out of ten on support and control, I’d rate the Adrenaline a 7 and the Kayano an 8.5.

Kayano 33 and Adrenaline GTS 25 - Outsoles
For more support from Brooks, the Glycerin GTS 23 is the more effective option. Check out our review of the Glycerin and Kayano here.
If value for money is your consideration, then the Adrenaline should provide everything required from a mildly supportive daily training shoe.

Adrenaline GTS 25 and Kayano 33 - Tongue and Lacing
For a plush, smooth-riding shoe, where you are less price-conscious, the Kayano is the best choice.
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